Marlin, mi piacerebbe un tuo parere sull'articolo che ti ho linkato giorni fa! Parla degli effetti preventivi sulle patologie androgeno dipendenti (iperplasia prostatica e aga) mediati dagli isoflavoni di soia e dai polifenoli del te, sia verde che nero. Il te nero ne esce notevolmente rivalutato.
In this study, black tea reduced serum levels of DHT, suggesting that black tea may have bioactive components
that inhibit the conversion of testosterone to DHT,
presumably via inhibition of 5-reductase in this SCID-LNCaP
animal model. It is unclear whether black tea theaflavins,
EGCG and/or other components are responsible for this function
in vivo.
On the other hand, green tea did not reduce the serum level
of DHT, but instead tended to increase it (P 0.076) (Fig.
2D), and we found that green tea treatment did not inhibit
tumor growth (Fig. 1A). Green tea contained more EGCG
than black tea (Table 1), and studies have shown that EGCG
inhibits the activity of 5-reductase (38). These results derived
from our animal model suggest that, although EGCG
may be a potent antitumor agent in green tea and inhibit
5-reducatase activity, green tea contains other constituents
that may counteract EGCG’s antitumor activity, in part by
counteracting its modulation of 5-reducatase activity. Further
research is required to identify these constituents and
study their effects and/or their interactions with other components
on prostate cancer. Our results demonstrate the importance
of evaluating the benefit of whole tea products,
rather than just isolated tea catechins or EGCG, on prostate
cancer prevention because other tea constituents may play
important roles.
E' anche uscito un altro studio sul te nero e il suo effetto sulla 5 alpha e il recettore AR (nei tessuti prostatici).
http://www.ncbi.nlm.nih.gov/entrez/...uids=14963012&query_hl=16&itool=pubmed_docsum
Inoltre ti linko questo abstract sull'anttività antiandrogena di lignani e isoflavonoidi (in particolare Biocanin A, genistenin e il tanto decantato equol)
http://www.ncbi.nlm.nih.gov/entrez/..._uids=7490559&query_hl=18&itool=pubmed_docsum
dovrebbero esserci integratori contenenti queste sostanze e utilizzati come terapia ormonale sostitutiva dalle donne in meno pausa. magari a dosaggi inferiori possono essere utili anche agli uomini... Tu fa uso di alimentari a base di soia?
]