per Marlin e Julien, parere

[isak borg]

Pistacchi e disfunzione erettile.

Int J Impot Res. 2011 Jan;23(1):32-8. Epub 2011 Jan 13.
Pistachio diet improves erectile function parameters and serum lipid profiles in patients with erectile dysfunction.
Aldemir M, Okulu E, Ne#351;elio#287;lu S, Erel O, Kay#305;gil O.

Department of 2nd Urology, Atatürk Teaching and Research Hospital, Ankara, Turkey.
Abstract
We investigated the effects of Antep pistachio on International Index of Erectile Function (IIEF) scores, penile color Doppler ultrasound (PCDU) parameters and serum lipid levels in patients with ED. A total of 17 married male patients with ED for at least 12 months were included in this prospective study. Patients were put on a 100#8201;g pistachio nuts diet for 3 weeks. IIEF and PCDU were evaluated before and after the pistachio diet. In addition, plasma total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride were measured before and after dietary modifications from all subjects. Mean IIEF-15 score was 36±7.5 before the diet and 54.2±4.9 after the diet (P=0.001). Similarly, an increase in all five domains of IIEF was observed after the diet (P<0.05). Mean peak systolic velocity values before and after the pistachio diet were 35.5±15.2 and 43.3±12.4#8201;cm#8201;s(-1), respectively (P=0.018). After the pistachio diet, TC and LDL levels decreased significantly, whereas HDL level increased (P=0.008, 0.007 and 0.001, respectively). We demonstrated that a pistachio diet improved IIEF scores and PCDU parameters without any associated side effects in patients with ED. Furthermore, the lipid parameters showed statistically significant improvements after this diet.

PMID: 21228801 [PubMed - in process]

 

[marlin]

Buoni e in espansione negli ipermercati, i pistacchi, ma forse i turchi hanno qualche interesse a promuoverli...(a parte quelli di Bronte, in Sicilia, la maggiore produzione viene da Iran e credo, proprio dalla Turchia).

Piuttosto, come mai punti sul magnesio citrato e non su altre forme (io sto usando il carbonato...) ?

Ciao

MA - r l i n

 

[romero]

Mah... direi che per fortuna tua non puoi seguire quella dieta
[]

 

[juliensorel]

http://www.ncbi.nlm.nih.gov/pubmed/21344933

 

[marlin]

Moolto interessante Julien, i vecchi isoflavoni di soia colpiscono ancora....[]

The verde con soia si confermerebbe così una grande abbinata antinvecchiamento.

Ciao

MA - r l i n

 

[isak borg]

Guardatevi questo centenario fenomenale http://www.youtube.com/watch?v=Gt_KcJYy36Y.
Notate le poche rughe, nonostante sia magro e fumatore. Con barba e capelli più corti e curati sembrerebbe ancora più giovane.

 

[marlin]

E' il nonno di de Grey...[] (questo fuma, l'altro beve...).

Ho sentito per caso la Lambertucci domenica parlare di de Grey...allucinante (se ci fosse il video ci sarebbe da scompisciarsi dal ridere... []).

Ciao

MA - r l i n

 

[jacob]

Tra l'altro c'è un suo video mentre corre la maratona..mentre gli altri fanno il pit-stop rifornendosi d'acqua, lui si ferma e si riempie un boccale di birra![]

 

[marlin]

....buon sangue, non mente....[]

MA - r l i n

 

[juliensorel]

copiate e incollate l'ure sequente -->

doi:10.1016/j.jbiotec.2011.01.019

Pare che siano riusciti a ricostruire de novo i capelli.

 

[andreat]

e' vecchiotta come notizia. Già i canonici 5 anni sono diventati 10.

Questa sugli omega 3 è fresca fresca e contribuisce a capire ancora di meno il soggetto.
http://www.ncbi.nlm.nih.gov/pubmed/21411616

 

[juliensorel]

la notizia non è vecchiotta ma di 2 mesi fa.

http://hubpages.com/hub/Stem-Cells-The-future-of-the-treatment-of-baldness

 

[isak borg]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Dec;27(6):1312-6.
Research on anti-aging effect of mouse placenta cells transplantation.
[Article in Chinese]
Li J, Zhang H, Liu G.
Institute of Hematonosis, Medical School, Jinan University, Guangzhou
510632, China. lijun19976@@@126.com
To determine the role of placenta cells allogeneic graft in mammalian
longevity, the 15-month-old female BALB/c mice (n = 50) were divided
into Control group (A), Short-term transplanted group (B) and Long-
term transplanted many times group (C). Their placentae (at 18 days of
gestation) were taken out and ground with 50-eye cell grit, and the
cells were intraperitoneally injected into the mice of B group and C
group three times at intervals of 10 days; then the cells were
transplanted into the mice of C group many times till the time of
death. The mice were evaluated by use of ultrasound-cardiogram;
autopsy; score of cardia, spleen, skin, lung, kidney; histopathology;
serum total superoxide dismutase activity, serum maleic dialdehyde
content, and serum glutathione peroxidase activity. The long-term
surviving stem cells were found to be located in many organ tissues of
B and C groups' mice with in situ Y chromosomal hybridization dyeing.
Median life span of B group mice was 1.7 times that of A group's after
transplantation, but there was no statistically significant difference
between B group and C group. Three months after transplantation, in B
group, the pathological developments of significant skin, cardia,
lung, and kidney were delayed; the retrogradation of heart function
was attenuated; the data on heart mass index (mass of heart/mass of
body), left ventricular mass and serum Maleic Dialdehyde content, and
on spleen mass index (mass of spleen/mass of body), left ventricular
diastolic volume, serum Total Superoxide Dismutase activity and serum
Glutathione Peroxidase activity, were all in a direction favourable to
B group (P < 0.05). These results were in line with the hypothesis, i.
e. longevity can be enhanced to some extent by transplantation of
placenta cells.
PMID: 21374985 [PubMed - in process]

 

[juliensorel]

IsaK, sul tuo ultimo link... in pratica ho sempre pensato che l'impianto di embrionali in un organismo adulto potesse avere un effetto anti-aging, anche se i problemi etici sollevabili (che beninteso secondo me NON sussistono) ostacolerebbero l'uso clinico. Peccato che lo studio non sia accessibile, ma si tratta di grandi risultati cioé di un 70% in più dell'aspettativa di vita media.

 

[marlin]

Io sono contro l'utilizzo delle staminali embrionali, ma la placenta contiene cellule totipotenti, ma di fatto non embrionali, quindi lo studio è interessante ed eticamente corretto (nel caso si applicasse la stessa tecnica all'uomo).

http://www.bioblog.it/2010/03/08/cellule-staminali-della-placenta-una-miniera-inutilizzata/20108855

Ciao

MA - r l i n

 

[andreat]

Citazione:la notizia non è vecchiotta ma di 2 mesi fa.

scusami ma devo dire che per chi è veramente calvo 2 mesi sono una eternità, ergo tu non hai molti problemi di capelli.

Mi ricordo che quando uscì la notizia si parlava di qualcosa di già commerciabile e ci fu letteralmente la caccia all'uomo(Lauster) per cercare di parlargli, ovviamente quando si creano tutte queste aspettative sicuramente si hanno delle delusioni.

Bello il post sulle staminali della placenta, però....qui non riusciamo ad ottenere due capelli, veramente sperate di poter ottenere una cosa decisamente più complicata come il prolungamento della vita?

 

[juliensorel]

>>la placenta contiene cellule totipotenti

Mah, pare che quando la blastocisti si impianta la totipotenza sia mantenuta fino alla seconda settimana di sviluppo (Barbieri, Carinci, Embriologia, pag. 130). Cmq è stato dimostrato che una cellula differenziata può essere riprogrammata a cellula pluripotente cambiando l'imprinting epigenomico. http://www.molecularlab.it/news/view.asp?n=6484 http://www.ilsole24ore.com/art/cultura/2010-12-19/queste-cellule-medicina-futuro-082426_PRN.shtml

 

[isak borg]

http://www.jstage.jst.go.jp/article/jaam/4/1/4_38/_article


Association of Aging with Minerals in Male Japanese Adults


Association of Aging with Minerals in Male Japanese Adults
Hiroshi Yasuda1), Kazuya Yoshida1), Hiroshi Tagai1), Katsumi Fukuchi1), Ryoichi Tokuda1), Toyoharu Tsutsui1) and Yoshikazu Yonei2)
1) Research Laboratory, La Belle Vie Inc.
2) Anti-Aging Medical Research Center, Doshisha University
(Received February 9, 2007)
(Accepted April 10, 2007)
(Published Online June 1, 2007)
Abstract
In order to examine possible association of aging with minerals, we measured hair concentrations of 24 bio-elements including essential minerals and toxic metals in over 1500 male Japanese adults aged 20-60 years. Several minerals were found to be significantly and positively or inversely correlated to aging. The most age-correlated element was mercury (Hg) with the highest regression coefficient of r = 0.417, followed by boron (B) (r = 0.189), potassium (K) (r = 0.186), arsenic (As) (r = 0.178), selenium (Se) (r = 0.153) and sodium (Na) (r = 0.131) with the p-value of p < 0.0000 for every element. Using the regression equation of Age = 13.9 Log Hg — 12.5 obtained, a 10-fold increase in mercury level was estimated to associate with a 13.9-year increment in aging. The most inverse-correlated mineral to aging was calcium (Ca) (r = -0.207), followed by magnesium (Mg) (r = -0.174), copper (Cu) (r = -0.147), and zinc (r = -0.105; p < 0.0001).
These findings suggest that some minerals contribute to aging and higher dietary mercury intake may be associated with acceleration of aging. Dietary intake of the competitive minerals against mercury, such as calcium, magnesium, cupper and zinc, may be useful for controlling aging in Japanese.

 

[andreat]

Potassio? Addirittura il selenio di cui è stabilita l'RDA.... non se ne può più di questi studi



Environ Health Prev Med. 2009 September; 14(5): 261–266.
Published online 2009 June 26. doi: 10.1007/s12199-009-0092-y. PMCID: PMC2728251

Copyright © The Japanese Society for Hygiene 2009

Metallomics study using hair mineral analysis and multiple logistic regression analysis: relationship between cancer and minerals

Hiroshi Yasuda,1 Kazuya Yoshida,1 Mitsuru Segawa,1 Ryoichi Tokuda,1 Toyoharu Tsutsui,1 Yuichi Yasuda,2 and Shunichi Magara3
1Research Laboratory, La Belle Vie Inc., 8-4 Nihonbashi-Tomizawacho, Chuo-ku, Tokyo, 103-0006 Japan
2Health Science Laboratory, Ni****okyo, 202-0001 Japan
3Somon-Hachioji Xxxxxx, Hachioji, 192-0082 Japan
Hiroshi Yasuda, Phone: +81-03-56142711, Fax: +81-03-36685001, Email: yasuda@LBV.jp.
Corresponding author.
Received December 25, 2008; Accepted May 14, 2009. Other Sections#9660;
Abstract

The objective of this metallomics study is to investigate comprehensively some relationships between cancer risk and minerals, including essential and toxic metals.Methods
Twenty-four minerals including essential and toxic metals in scalp hair samples from 124 solid-cancer patients and 86 control subjects were measured with inductively coupled plasma mass spectrometry (ICP-MS), and the association of cancer with minerals was statistically analyzed with multiple logistic regression analysis.

Results
Multiple logistic regression analysis demonstrated that several minerals are significantly correlated to cancer, positively or inversely. The most cancer-correlated mineral was iodine (I) with the highest correlation coefficient of r = 0.301, followed by arsenic (As; r = 0.267), zinc (Zn; r = 0.261), and sodium (Na; r = 0.190), with p < 0.01 for each case. In contrast, selenium (Se) was inversely correlated to cancer (r = #8722;0.161, p < 0.05), followed by vanadium (V) (r = #8722;0.128). Multiple linear regression value was highly significantly correlated with probability of cancer (R2 = 0.437, p < 0.0001), and the area under the receiver-operating characteristic (ROC) curve was calculated to be 0.918. In addition, using contingency table analysis and the chi-square test, the precision of discrimination for cancer was estimated to be 0.871 (chi-square = 99.1, p < 0.0001).Conclusions
These findings suggest that some minerals such as arsenic, selenium, and probably iodine, zinc, sodium, and vanadium contribute to regulation of cancer and also that metallomics study using multiple logistic regression analysis is a useful tool for estimating cancer risk.

 

[marlin]

Sono due studi interessanti e che possono confermarci alcune cose immaginabili, ammesso che ci siano delle reali correlazioni con invecchiamento e cancro (che per certi versi si oppongono: tessuti statici e senescenti contro tessuti in rapida proliferazione).

Il mercurio è sempre stato considerato un cattivone (anche per questo si insiste su olio di pesce certificato IFOR...[]), mentre del selenio molti studi hanno messo in evidenza come gli eccessi possano essere nocivi quanto la carenza.
Del potassio non saprei, mentre lo zinco, spesso demonizzato, pare barcamenarsi bene tra i due studi (positivo contro l'invecchiamente e ovviamente - proliferazione cellulare - meno positivo per il cancro....).

Lo iodio mi pare possa andare proprio in questa direzione ossia aiuta a rinnovare i tessuti, si pensino solo il ruolo che svolge per gli ormoni tiroidei.

Purtroppo non si può avere tutto, almeno al momento attuale: l'invecchiamento sembra permettere di tirare avanti con la vita anche perché prova a contrastare, ponendo freno al rinnovo cellulare, l'insorgere dei tumori.

Ciao

MA - r l i n