https://www.intechopen.com/books/hair-and-scalp-disorders/androgenic-alopecia-cross-talk-between-cell-signal-transduction-pathways
scaricare il PDF.
Bel lavoro aggiornato e recente, dedicato a quelli che pensano che la soluzione dell'aga sia semplice e che il DHT non c'entri nulla...
Peraltro ritrovo una mia convinzione nelle conclusioni:
NR4A2, EGR1, HES1, and NR4A2 had remarkable difference in expression between bald and nonbald DP cell samples. Unfortunately,role of these proteins was acquired in cancer-related studies that make them hardly applicable to the hair follicle research.
da cui, volendo, la frase conclusiva:
The obtained results suggest that AGA dermal papilla in frontal scalp area differs from occipital ones unlikely due to downregulation of proliferation and increased expression of catagen triggers, but rather due to reduced expression of anagen triggers.
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MA - r l i n