Citazione:Messaggio inserito da Marlin
Giusto Klaus; io alla fine ho seguito il consiglio di Julien e prendo quello della Long Life che sono capsule (n°50) da 600 mg con the verde in foglia per 300 mg titolato al 95% (285 mg) in polifenoli totali di cui 80% in catechine (240 mg) con epigallocatechinagallato (EGCG, che è quello che più conta) al 40% (120 mg). Costo sui 12 euro.
Non so se è il più potente in commercio, ma almeno so cosa sto prendendo[
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In commercio si trova, credo solo negli USA, un vero e proprio farmaco con solo EGCG. Ma secondo me è un errore puntare tutto su questa molecola. IL tè nero secondo uno studio del 2003 riduce le concentrazioni sieriche di DHT, mentre il tè verde in questo senso addirittura tende ad aumentarle. D'altra parte il te verde riduce le concentrazioni sieriche di DHT in combinazione con gli isoflavoni di soia. RIporto il passo conclusivo dello studio..
Androgen is a prerequisite for the development of benign
prostatic hyperplasia and prostate cancer. In the prostate,
testosterone is rapidly and irreversibly converted to a more
biologically active metabolite, DHT, by catalysis of 5-reductase.
EGCG has been shown to inhibit the growth of prostate
cancer cells in vitro (36) and in vivo (37) through mechanisms
that might involve inhibition of type I 5-reductase
(37). In this study, black tea reduced serum levels of DHT
(Fig. 2D), suggesting that black tea may have bioactive components
that inhibit the conversion of testosterone to DHT,
presumably via inhibition of 5-reductase in this SCID-LNCaP
animal model. It is unclear whether black tea theaflavins,
EGCG and/or other components are responsible for this function
in vivo.
On the other hand, green tea did not reduce the serum level
of DHT, but instead tended to increase it (P 0.076) (Fig.
2D), and we found that green tea treatment did not inhibit
tumor growth (Fig. 1A). Green tea contained more EGCG
than black tea (Table 1), and studies have shown that EGCG
inhibits the activity of 5-reductase (38). These results derived
from our animal model suggest that, although EGCG
may be a potent antitumor agent in green tea and inhibit
5-reducatase activity, green tea contains other constituents
that may counteract EGCG’s antitumor activity, in part by
counteracting its modulation of 5-reducatase activity. Further
research is required to identify these constituents and
study their effects and/or their interactions with other components
on prostate cancer. Our results demonstrate the importance
of evaluating the benefit of whole tea products,
rather than just isolated tea catechins or EGCG, on prostate
cancer prevention because other tea constituents may play
important roles.
Green tea combined with SPC reduced total testosterone
and DHT levels (Fig. 2A, B), suggesting that interactive
modulation of androgen levels is one of the important mechanisms
for the synergistic prevention of prostate cancer progression
by the soy/green tea combination. This study supports
the use of appropriate combinations of bioactive dietary
agents, such as soy and tea, as effective nutritional regimens for
prostate cancer prevention and treatment.
In summary, both black tea and green tea inhibited tumorigenicity
rates of LNCaP tumors. Although tea contains bioactive
catechins, it contains other components that contribute
to its anticancer activity. Black tea inhibited prostate cancer
tumorigenicity, metastasis and final tumor weight in association
with a reduced serum level of DHT. Green tea did not
reduce final tumor weight in association with a tendency to
increase serum androgen levels.
The combination of soy phytochemicals and tea synergistically
inhibited tumorigenicity, final tumor weight and metastasis
to lymph nodes in vivo. In particular, the synergistic
inhibition by the green tea and SPC combination on tumor
progression and metastasis is associated with effective reductions
of serum levels of both testosterone and DHT. This study
supports further investigations using soy and tea combinations
as effective nutritional regimens for prevention of prostate
cancer. It shows for the first time that the Asian diet effectively
prevents prostate cancer progression in part via synergistic
interactions of bioactive components.
http://www.nutrition.org/cgi/reprint/133/2/516
Uno studio apparso un anno dopo sembra confermare il potere antiandrogeno del te nero, in particolare di un suo composto, il TF3.
http://www.ncbi.nlm.nih.gov/entrez/...uids=14963012&query_hl=10&itool=pubmed_docsum
Sul potere antiossidativo del tè nero leggere
http://www.nutrition.org/cgi/reprint/131/9/2248
insomma se non fosse chiaro, consiglio di bere un po' del bistrattato te nero assieme al tanto osannato te verde
