Little documentation on the bioavailability of the mineral salts of orotic acid has been submitted, but one study reveals that the bioavailability of zinc from zinc orotate is comparable to that of zinc from another organic source as well as an inorganic salt. The Panel concludes that this will probably also be the case for the bioavailability of the cations from the other orotate salts, for which no documentation has been supplied.
http://www.efsa.europa.eu/it/efsajournal/doc/1187.pdf
http://www.efsa.europa.eu/it/efsajournal/doc/1187.pdf
