Conosciuto (?) anche come kiwi arguta (actinidia arguta).
C'è un patent in cui viene utilizzato l'estratto (per via orale) per alopecia e dermatite seborroica. Qui un estratto del patent in cui riferiscono i risultati delle sperimentazioni:
Experimental Example 1 Inhibiting Activity on the Formation of Blood DHT
1-1. Effect of Polar Soluble Extract of Hardy Kiwi on the Concentration of Blood DHT
To confirm the inhibition effect of hardy kiwifruit extract on the concentration of blood DHT, the water extract and ethanol extract of hardy kiwi were administrated into mice and the concentration of blood DHT were determined by following procedure;
Male C57BL/6 mice, aged 6 weeks (Seoul national university animal experimental center) were acclimated to the environment for 1 week. After 7 weeks, 16 mice were divided into 4 groups and each group was orally administered with 100 ul of the hardy kiwifruit water extract (1500 ug/mouse/day), 100 ul of the hardy kiwifruit ethanol extract (1500 ug/mouse/day), 100 ul of finasteride (100 ug/mouse/day) and 100 ul of drinking water (100 ug/mouse/day) for 3 weeks, respectively. After mice were sacrificed and the blood serum and spleen organ were collected therefrom, the concentration of blood DHT was measured by ELISA (IBL-Hamburg GmbH) method.
As shown in the FIG. 4, the concentration of blood DHT in groups administered with hardy kiwifruit extracts showed a decrease of about 90% with similar to groups administered with finasteride.
1-2. Effect of Non-Polar Soluble Extract of Hardy Kiwi on the Concentration of Blood DHT
To measure the concentration of blood DHT of C57BL/6 mice, chloroform soluble fraction, ethyl acetate soluble fraction and water soluble fraction prepared in above Example 2 were subjected to the identical experiment disclosed in above Experimental Example 1-1.
50 ul of the chloroform soluble fraction, ethyl acetate soluble fraction and water soluble fraction were administrated to C57BL/6 mice, respectively. 100 ul of drinking water was administrated as control.
As shown in the FIG. 5, the concentration of blood DHT showed a decrease of about 95% in the group administered with the ethylacetate double fraction of hardy kiwifruit and a slight decrease in the group administered with the water soluble fraction of hardy kiwifruit. However, it was not affected in the group administrated with the chloroform soluble fraction of hardy kiwifruit.
1-3. Effect of Silica Gel Column Chroma
C'è un patent in cui viene utilizzato l'estratto (per via orale) per alopecia e dermatite seborroica. Qui un estratto del patent in cui riferiscono i risultati delle sperimentazioni:
Experimental Example 1 Inhibiting Activity on the Formation of Blood DHT
1-1. Effect of Polar Soluble Extract of Hardy Kiwi on the Concentration of Blood DHT
To confirm the inhibition effect of hardy kiwifruit extract on the concentration of blood DHT, the water extract and ethanol extract of hardy kiwi were administrated into mice and the concentration of blood DHT were determined by following procedure;
Male C57BL/6 mice, aged 6 weeks (Seoul national university animal experimental center) were acclimated to the environment for 1 week. After 7 weeks, 16 mice were divided into 4 groups and each group was orally administered with 100 ul of the hardy kiwifruit water extract (1500 ug/mouse/day), 100 ul of the hardy kiwifruit ethanol extract (1500 ug/mouse/day), 100 ul of finasteride (100 ug/mouse/day) and 100 ul of drinking water (100 ug/mouse/day) for 3 weeks, respectively. After mice were sacrificed and the blood serum and spleen organ were collected therefrom, the concentration of blood DHT was measured by ELISA (IBL-Hamburg GmbH) method.
As shown in the FIG. 4, the concentration of blood DHT in groups administered with hardy kiwifruit extracts showed a decrease of about 90% with similar to groups administered with finasteride.
1-2. Effect of Non-Polar Soluble Extract of Hardy Kiwi on the Concentration of Blood DHT
To measure the concentration of blood DHT of C57BL/6 mice, chloroform soluble fraction, ethyl acetate soluble fraction and water soluble fraction prepared in above Example 2 were subjected to the identical experiment disclosed in above Experimental Example 1-1.
50 ul of the chloroform soluble fraction, ethyl acetate soluble fraction and water soluble fraction were administrated to C57BL/6 mice, respectively. 100 ul of drinking water was administrated as control.
As shown in the FIG. 5, the concentration of blood DHT showed a decrease of about 95% in the group administered with the ethylacetate double fraction of hardy kiwifruit and a slight decrease in the group administered with the water soluble fraction of hardy kiwifruit. However, it was not affected in the group administrated with the chloroform soluble fraction of hardy kiwifruit.
1-3. Effect of Silica Gel Column Chroma