NON so se vi era sfuggito questo riguardo finasteride e giovani ragazzi con varicocele.
su questo studio trovato (uno dei pochi che abbia messo in relazione fina con stati di ipofertilita' si era osservato che su alcuni ragazzi giovani con varicocele che assumevano fina 1mg/die per alopecia androgenetica lo spermiogramma era compromesso negativamente e quando hanno smesso l'assunzione e' molto migliorato..
Rev Hosp Clin Fac Med Sao Paulo. 2004 Aug;59(4):203-5. Epub 2004 Sep 9. Related Articles, Links
Finasteride-associated male infertility.
Glina S, Neves PA, Saade R, Netto NR Jr, Soares JB, Galuppo AG.
Human Reproduction Unit, Albert Einstein Jewich Hospital, Sao Paulo, SP, Brazil. glinas@terra.com.br
Finasteride is a potent and specific inhibitor of the 5alpha-reductase enzyme in men. Clinical studies have shown that finasteride 1mg/day is effective for promoting hair growth in men with male pattern hair loss. However, there is a concern about the use of finasteride, especially in young fertile patients, because of its action on testosterone metabolism. This paper describes 3 cases of young patients who had very poor seminal quality during finasteride treatment (1 mg/day), and their seminal quality greatly improved after cessation of finasteride treatment.They presented with a left varicocele. We hypothesize that finasteride may not dramatically change the spermatogenesis process in healthy men, but in patients with conditions related to infertility, an amplification of the negative influence of finasteride could occur. Future studies should be done to clarify the extent of the effect of finasteride in patients fertility problems.
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