Suzhou, April 18, 2024 - Kintor Pharmaceutical Limited (“Kintor Pharma”, HKEX: 9939), a clinical-stage biotechnology company developing innovative small molecules and biological therapeutics, regrets to announce the unexpected outcome of the Phase 2 clinical trials for its in-house developed first-in-class proteolysis targeting chimera (PROTAC) compound GT20029 in China for the treatment of male androgenetic alopecia (AGA).
Despite promising preclinical data and the completion of enrollment of 180 patients across 12 clinical research centers in China, the Phase 2 clinical trials for GT20029 have concluded with unexpected outcomes. The drug failed to meet the desired efficacy endpoints in treating male AGA patients, as compared to placebo, resulting in an unforeseen setback for the company.
Dr. Youzhi Tong, founder, Chairman, and Chief Executive Officer of Kintor Pharma, expressed his disappointment, stating, “We were optimistic based on the promising results from earlier trials, but unfortunately, the Phase 2 trials did not yield the expected outcome. We remain committed to our mission of developing effective treatments for hair loss and other dermatological conditions, and we will continue to explore other avenues in our research efforts.”
Dr. Tong also addressed the individuals following Kintor for potential solutions to their hair loss, saying, "We understand the anticipation of those who have been following our progress in the development of hair loss treatments. While we share in their disappointment with these results, we urge them to remain patient and resilient. In the meantime, they may wish to perfect their comb over technique while we work diligently to find novel solutions."
The company extends its gratitude to all the principal investigators, clinical research centers, and staff involved in the Phase 2 clinical trials of GT20029 and reaffirms its dedication to bringing innovative therapies to patients worldwide.
A voi.