Fifth International Congress of Hair Research
- Thread starter grillo
- Start date
Ci sono speech di ricercatori un pò su ogni fronte.
Dall'abstract di intercytex c'è da pensare un pò male ma nn ho voglia di tirar conclusioni..(suggerimento-> importanza dei cheratinociti per le dp )
Notare che Washenik tiene un discorso su Surgical treatment of hair loss in contrapposizione ad HM.
Cotsarelis : discorso da 15 minuti.
Confermata l'importanza della modulazione del bmp-signal (ma nello specifico di neosh101 NESSUN accenno ).
Dutasteride non nominata.
Dall'abstract di intercytex c'è da pensare un pò male ma nn ho voglia di tirar conclusioni..(suggerimento-> importanza dei cheratinociti per le dp )
Notare che Washenik tiene un discorso su Surgical treatment of hair loss in contrapposizione ad HM.
Cotsarelis : discorso da 15 minuti.
Confermata l'importanza della modulazione del bmp-signal (ma nello specifico di neosh101 NESSUN accenno ).
Dutasteride non nominata.
Ti capisco[
].
Comunque è pieno zeppo di lavori interessanti (ma qualcosa del genere Julien lo aveva già postato, solo che non ricordo se coincideva in tutto o solo in parte con questo documento, ricordo solo che anche lì c'era l'estratto di eucalipto...), quindi piuttosto estraiamo i singoli abstact dei lavori e commentiamoli, magari nelle sezioni più indicate per ciascuno argomento.
Ciao
MA - r l i n
].Comunque è pieno zeppo di lavori interessanti (ma qualcosa del genere Julien lo aveva già postato, solo che non ricordo se coincideva in tutto o solo in parte con questo documento, ricordo solo che anche lì c'era l'estratto di eucalipto...), quindi piuttosto estraiamo i singoli abstact dei lavori e commentiamoli, magari nelle sezioni più indicate per ciascuno argomento.
Ciao
MA - r l i n
per quanto riguarda l'intercytex.... era presente anche questo sui proto hair..
mi domando perhè nn seguano anche questa strada! oltre al TRC
Proto-Hair Development In Vitro
Qiao, Jizeng; Turetsky, Anya; Teumer, Jeff; Intercytex, Woburn,
MA, USA
Objectives: To develop an in vitro system in which to grow
partially formed hair follicles that, when implanted, will
continue to develop into fully formed hairs.
Approach: Hair follicle cells were prepared by enzymatic
digestion followed by two sequential sievings. Cell
aggregates were made and cultured to allow proto-hair
development in vitro. Both freshly made and cultured
aggregates were implanted onto an immune deficient
mouse ear skin to test for mature hair development.
Results: Aggregates made with freshly isolated cells
consistently developed hairs after implantation. Aggregates
cultured in vitro consistently developed proto-hairs,
which are partially formed hair follicles with distinctive
morphology. Such in vitro-produced proto-hairs further
developed into mature hairs after implantation. Most
implants developed hairs that grew out of the skin, while
some developed underneath the skin surface but failed
to emerge. Histological studies confirmed immature hair
structures formed from cell aggregates during cultivation
in vitro.
Conclusion:
• We demonstrated that proto-hairs can be produced in
vitro from cultured cells.
• We proposed a concept of the immature ‘proto-hair’ as an
option for clinical transplantation.
mi domando perhè nn seguano anche questa strada! oltre al TRC
Proto-Hair Development In Vitro
Qiao, Jizeng; Turetsky, Anya; Teumer, Jeff; Intercytex, Woburn,
MA, USA
Objectives: To develop an in vitro system in which to grow
partially formed hair follicles that, when implanted, will
continue to develop into fully formed hairs.
Approach: Hair follicle cells were prepared by enzymatic
digestion followed by two sequential sievings. Cell
aggregates were made and cultured to allow proto-hair
development in vitro. Both freshly made and cultured
aggregates were implanted onto an immune deficient
mouse ear skin to test for mature hair development.
Results: Aggregates made with freshly isolated cells
consistently developed hairs after implantation. Aggregates
cultured in vitro consistently developed proto-hairs,
which are partially formed hair follicles with distinctive
morphology. Such in vitro-produced proto-hairs further
developed into mature hairs after implantation. Most
implants developed hairs that grew out of the skin, while
some developed underneath the skin surface but failed
to emerge. Histological studies confirmed immature hair
structures formed from cell aggregates during cultivation
in vitro.
Conclusion:
• We demonstrated that proto-hairs can be produced in
vitro from cultured cells.
• We proposed a concept of the immature ‘proto-hair’ as an
option for clinical transplantation.