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According to the Cost study, PGD2-treated hair was significantly shortened, while PGD2's derivative, 15-dPGJ2, completely inhibited hair growth. What are some ways we can reduce 15-dPGJ2? In one study on mice (nothing to do with hairloss)showed that PGH2 is first converted to PGD2 by lipocalin-type PGD2 synthase (L-PGDS) or hematopoietic (H)-PGDS, which then undergoes sequential non-enzymatic dehydration reactions to form 15-deoxy-#916;12,14-PGJ2 (15d-PGJ2). The results showed that toxicity of 15d-PGJ2 to mOP cells is related to intracellular GSH levels. An increase in glutathione reduced the effect of 15d-PGJ2 in MOP cells.
https://www.pointofreturn.com/glutathione.html
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