Finasteride e occhi

propp

Utente
26 Gennaio 2011
275
0
265
Devo dire che questa notizia non l'avevo ancora sentita

uno studio parla di uno strano side.
Possibile correlazione tra fina e cataratta e IFIS ?

Forse quelli che lamentano i sides più assurdi non sono sempre pazzi


Finasteride-associated cataract and intraoperative floppy-iris syndrome.

A 47-year-old man who had been using finasteride for male pattern alopecia for 4 years complained of progressive bilateral blurring of vision. His general health had been good, and he was not on any other long-term medication. Examination showed bilateral anterior subcapsular cataracts. Phacoemulsification and insertion of intraocular lenses were performed, and both eyes showed features of intraoperative floppy-iris syndrome (IFIS), including undulation and billowing of the iris, iris prolapse, and pupil constriction. We believe the use of finasteride can be associated with cataract formation and IFIS. Ophthalmologists and physicians prescribing finasteride should be aware of this possible association
http://www.ncbi.nlm.nih.gov/pubmed/21555201


 

propp

Utente
26 Gennaio 2011
275
0
265
Devo dire che questa notizia non l'avevo ancora sentita

uno studio parla di uno strano side.
Possibile correlazione tra fina e cataratta e IFIS ?

Forse quelli che lamentano i sides più assurdi non sono sempre pazzi


Finasteride-associated cataract and intraoperative floppy-iris syndrome.

A 47-year-old man who had been using finasteride for male pattern alopecia for 4 years complained of progressive bilateral blurring of vision. His general health had been good, and he was not on any other long-term medication. Examination showed bilateral anterior subcapsular cataracts. Phacoemulsification and insertion of intraocular lenses were performed, and both eyes showed features of intraoperative floppy-iris syndrome (IFIS), including undulation and billowing of the iris, iris prolapse, and pupil constriction. We believe the use of finasteride can be associated with cataract formation and IFIS. Ophthalmologists and physicians prescribing finasteride should be aware of this possible association
http://www.ncbi.nlm.nih.gov/pubmed/21555201


 

propp

Utente
26 Gennaio 2011
275
0
265
Devo dire che questa notizia non l'avevo ancora sentita

uno studio parla di uno strano side.
Possibile correlazione tra fina e cataratta e IFIS ?

Forse quelli che lamentano i sides più assurdi non sono sempre pazzi


Finasteride-associated cataract and intraoperative floppy-iris syndrome.

A 47-year-old man who had been using finasteride for male pattern alopecia for 4 years complained of progressive bilateral blurring of vision. His general health had been good, and he was not on any other long-term medication. Examination showed bilateral anterior subcapsular cataracts. Phacoemulsification and insertion of intraocular lenses were performed, and both eyes showed features of intraoperative floppy-iris syndrome (IFIS), including undulation and billowing of the iris, iris prolapse, and pupil constriction. We believe the use of finasteride can be associated with cataract formation and IFIS. Ophthalmologists and physicians prescribing finasteride should be aware of this possible association
http://www.ncbi.nlm.nih.gov/pubmed/21555201


 

sigma82

Utente
12 Agosto 2009
281
0
265
Premetto che non sono assolutamente daccordo all'assunzione della finasteride avendola presa per 6 mesi.
Però sinceramente non so più che pensare, ci si sta accanendo, ci si sta guadagnando a screditare la molecola?
Davvero adesso stanno venendo fuori cose assurde!!! Mah...
Io una cosa non riesco a capire, come fanno a correlare con certezza la finasteride, in questo caso, con la possibile cataratta in uomo!! Non può succedere a prescindere dall'assunzione della finasteride la formazione di una cataratta?
E' una malattia abbastanza comune con l'avanzare dell'età, a 47 anni poi!
Vorrei capire alla base dello studio che esami scientifici ci sono per darne la certezza.
Veramente sta diventando la causa di tutti i mali a questo punto.
 

propp

Utente
26 Gennaio 2011
275
0
265
Però sinceramente non so più che pensare, ci si sta accanendo, ci si sta guadagnando a screditare la molecola?
Davvero adesso stanno venendo fuori cose assurde!!! Mah...

Cercando un pochino vedo che cmq vi sono altri studi non recenti.

in ogni caso devo dire che, personalmente, come side mi sembra molto raro. Anche nei report aneddotici non compare quasi mai


Propecia-associated bilateral cataract.
Chou SY, Kao SC, Hsu WM.
Abstract
A 43-year-old man presented suffering from decreasing vision in both eyes for 3 months. The patient's visual acuity was 6/20 (non-corrected) in the right eye and 6/10 (-1.75/-1.00 x 91) in the left. Ocular examination of both eyes revealed anterior subcapsular opacities of both lenses with the right eye being more severe than the left. He had been taking finasteride (Propecia; Merck, Sharp and Dohme) at 1 mg/day for 3 years to treat early stage of androgenic alopecia. It was highly suspected that finasteride was associated with the anterior subcapsular opacity on the lens, and the patient therefore discontinued use of finasteride. He underwent uneventful cataract extraction surgery and intraocular lens implantation of the right eye. One month after cataract surgery in the right eye, the best-corrected visual acuity was right 6/6 (-1.25) and left 6/10 (-2.00/-0.50 x 100). To the best of the authors' knowledge, this is the first reported case of Propecia-associated cataract.
http://www.ncbi.nlm.nih.gov/pubmed/14746605


Intraoperative floppy-iris syndrome and finasteride intake.
Issa SA, Dagres E.
Department of Ophthalmology, James Cook University Hospital, Middlesbrough, Cleveland TS4 3BW, United Kingdom.
Abstract
We report 2 male patients who had bilateral cataract surgery. Both patients had features of the intraoperative floppy-iris syndrome (IFIS) in both eyes, and both were taking oral finasteride for the management of benign prostatic hyperplasia (BPH). We conclude that finasteride can be associated with IFIS, so it is important to take detailed medical histories of patients having cataract surgery, paying attention to a history of BPH and its treatment.
http://www.ncbi.nlm.nih.gov/pubmed/18053919